Gnome with extensions like dock to panel and arcmenu (need those two at least but with them its pretty near perfect), or kde plasma are your best bet, plasmas almost too easily customizable I find myself messing with it a lot.

If you want immutable go bazzite, cachyos I initially dualbooted before erasing my whole drive and reinstalling because I didnt want to deal with windows ever again, piracy is harder, other than that everything I use works.

Cachyos works perfectly fine for me, it installs all the packages has a cachyos steam compatibility thing, just works for everything, had to install blender off the official site because the aur package has issues and had to grab those amd drivers seperately but thats about it

I havent used it in 15 years and will prob keep that up, used to weirdly love photo editing

I use porkbun and you get cloudflare through them, not sure to what extent, porkbuns just cheaper, I like their ui, straightforward, everything you need on one screen.